BIO5065 - Cyto and Histopathology

Objectives:

On successful completion of the module, students will be able to:

LO1 - Prepare cells and tissues for microscopic examination using histological and cytological techniques for gross structure and ultrastructure of normal cells or tissues and for identification of the structural changes which may occur during disease.

LO2 - Apply knowledge of reproductive science, including infertility and embryology in diagnosis and monitoring using cytological and histological techniques.

LO3 - Utilise the principles and applications of visualisation and imaging techniques, to select the most appropriate aid to diagnosis and treatment.

LO4 - Apply the principles and practice of histological and cytological testing in a practical setting.

Content:

This module explores the key aspects of cytopathology and histopathology used to help diagnose and manage disease through analysis of cell and tissue samples. The module includes how measurements are performed and set up to ensure the reliability of results. A major section of the module outlines the most common tests, plus the disease processes that they can be used to identify and manage. The module also covers other methods that can be combined with cellular pathology to aid diagnosis, such as scanning and imaging techniques. Case studies are used to illustrate key processes for the use of the techniques in the diagnosis of a range of disorders where cell and tissue samples can be obtained from biopsy.

The content of this module has been mapped to the IBMS QAA Benchmark requirements for:
- Cellular Pathology (Clinical Laboratory Specialism) including gross structure and ultrastructure of normal cells and tissues and the structural changes which may occur during disease; reproductive science, including infertility and embryology; preparation of cells and tissues for microscopic examination; principles and applications of visualisation and imaging techniques, including microscopy, to aid diagnosis and treatment selection.

- Quality Management including interpretation of quality control standards (QC); importance of quality assurance and pre-analytical variables; understanding of the importance of external quality assessment (EQA); including basic knowledge of the purpose of quality policy, audits, standard operating procedures, training and competency documentation, error logging and incident reporting, validation and verification, and reagent inventories; laboratory accreditation to include basic awareness of UK Accreditation Service (UKAS) and International Organisation for Standardisation (ISO) standards.

Learning and Teaching Information:

A series of 10 x 2 hr lecture sessions (1 per week) covering the key concepts of cytopathology and histopathology will be delivered.
A total of 5 x 2 hr laboratory practical sessions will be given to introduce you to key cytopathology and histopathology and techniques.
A total of 10 x 1 hr tutorials (1 per week) will be provided to support the lecture and practical content, assessments, and general wellbeing.

Lectures
Hours: 20
Intended Group Size: Full Cohort (40)

Practical sessions
Hours: 10
Intended Group Size: Full Cohort (40)

Tutorials
Hours: 10
Intended Group Size: Max 20

Guided independent study
Hours: 110

Further detail relating to assessment

Assessment tasks are designed to measure the extent to which you have satisfied the Level Learning Outcomes for your programme. Some modules, for example where there are professional body (PSRB) requirements, will also test for module-specific skills and knowledge.

Further details of assessment are available in the Assessment Handbook for your programme and in Assessment Briefs provided by Module Tutors.

Post lecture, tutorial and practical session activities submitted through Moodle will facilitate ongoing formative assessment opportunities via lecturer or peer feedback.

The Integrated Practical report will be set at the start of Semester 2 and will require you to analyse data generated in the selected practical sessions for this module, the Molecular Diagnostics module, and the Clinical Biochemistry module. You will then relate the data to the Clinical Biochemistry, Cytopathology, Histopathology and Molecular Diagnostics covered in the associated lectures and tutorials. The report will be submitted Mid-Semester 2.

The Pathology Portfolio assessment will take the form of an annotated bibliography covering five peer reviewed data papers, relevant to cytopathology and histopathology. Each paper will be from a list of specified disease areas that will be provided at the start of Semester 2. Tutorial sessions will cover annotation of example papers in each of the disease areas on a weekly basis. You will be advised to annotate a paper of your choice in the specified disease area during guided independent study for that week. The portfolio of all the annotated bibliographies will be collated and submitted at the end of Semester 2.

The Institute of Biomedical Science (IBMS) professional body requires students to achieve a pass mark in all assessment components for modules that cover the clinical laboratory sciences subject areas including this one. Since laboratory practical sessions contribute towards assessments these sessions should be considered compulsory. Condonement/compensation will not be permitted for this module, which contributes significantly to the benchmark statement and has learning outcomes that cannot be evidenced elsewhere for the accreditation of the degree.

Assessment:

Fact File

Module Coordinator - PRS_CODE=
Level - 5
Credit Value - 15
Pre-Requisites - NONE
Semester(s) Offered -

Click here to go back to previous page