BIO5043 - Haematology & Transfusion Science

Objectives:

On successful completion of the module, students will be able to:
Distinguish and contrast the features of a variety of diseases caused by abnormalities of the bone marrow, blood cells and plasma components.
Evaluate methods and interpret results from analysis of blood cells and coagulation factors in haematological diseases.
Differentiate and compare the features of a variety of pathological conditions encountered in haematology.
Discuss the causes, mechanisms and treatment of transplantation immunoreactivity.
Apply a broad understanding of transfusion science.
Evaluate the principles of histocompatibility and immunogenetics in transplantation and blood transfusion.

Content:

The module covers the major Haematological diseases (anaemias, haematological malignancies, haemorrhagic and thrombotic diseases) plus Transfusion science (the main blood group systems, transfusion reactions, haemolytic diseases). Histocompatibility and immunogenetics are also covered in terms of evolution, function, and genetics plus their role in transplantation and blood transfusion. Laboratory techniques for sample collection, cell identification and counting, measurement of haemoglobin and its variants, blood typing plus coagulation tests are also studied with appropriate practical sessions.

The content of this module has been mapped to the IBMS QAA Benchmark requirements for:
- Haematology (Clinical Laboratory Specialism) including structure, function and production of blood cells; regulation of normal haemostasis; blood cell morphology - identification of normal white blood cells and common red blood cell abnormalities; nature and diagnosis of anaemias, haematological malignancies, haemorrhagic and thrombotic disease; principles and practice of haematological techniques used for screening, diagnosis, treatment and monitoring of disease.
- Transfusion Science (Clinical Laboratory Specialism) including interpretation of blood groups, causes of blood group anomalies, antibody screening; genetics, inheritance, structure and role of red cell antigens; immune-mediated destruction of blood cells; preparation, storage and use of blood components; patient blood management; selection of appropriate blood components for transfusion and possible adverse effects.

Learning and Teaching Information:

A series of 18 x 2h lecture sessions covering the key Haematological diseases and transfusion science principals will be used. A total of 6 x 3h practical sessions will be used to support the lectures and demonstrate key techniques used in the assessment of blood. A total of 20 x 1h tutorials (2 per week) will be used to support the Lecture teaching plus assessments.

Lectures
Hours: 36
Intended Group Size: Full Cohort

Practical sessions
Hours: 18
Intended Group Size: Full Cohort

Tutorials
Hours: 20
Intended Group Size: Max 20

Guided independent study
Hours: 226

Further details relating to assessment
Post lecture, tutorial and practical session activities submitted through Moodle will facilitate ongoing formative assessment opportunities via lecturer or peer feedback.

The Blood Practical report will be set at the start of Semester 2 will be set at the start of Semester 2, with students informed which practical sessions undertaken during the module have been selected. The assessment is based on students answering questions and analysing data generated in each of the selected practical sessions. Questions and data to be analysed will be set as part of each of the selected practical sessions and students will be required to complete the answers to the questions plus data analysis as guided independent study and then submit the report mid-semester 2.

The Exam will take place at the end of Semester 2 and will involve students being set a series of questions about the key aspects of haematology and transfusion science covered in the lecture and tutorial teaching.

Other Information
The Institute of Biomedical Science (IBMS) professional body requires students to achieve a pass mark in all assessment components for modules that cover the clinical laboratory sciences subject areas including this one. Since laboratory practical sessions contribute towards assessments these sessions should be considered compulsory. Condonement/compensation will not be permitted for this module, that contributes significantly to the benchmark statement and have learning outcomes that students achieve that cannot be evidenced elsewhere for the accreditation of the degree.

Assessment:

Fact File

Module Coordinator - PRS_CODE=
Level - 5
Credit Value - 30
Pre-Requisites - NONE
Semester(s) Offered -

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