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BIO5023 - Clinical Immunology & Microbiology

Objectives:

On successful completion of the module, students will be able to:
Implement knowledge of the function and measurement of the effectors of the immune response plus the causes and consequences of abnormal immune function, neoplastic diseases, and transplantation reactions together with their detection, diagnosis, treatment and monitoring.
Apply the principles and practice of immunological techniques used for screening, diagnosis, treatment and monitoring of disease, prophylaxis and immunotherapy.
Explain and compare the different mechanisms of pathogenicity of a range of pathogens affecting different body sites.
Apply and synthesize knowledge and understanding of the principles and practice of techniques used for screening, diagnosis, treatment, and monitoring of a range of infectious diseases, involving a range of methods to detect and identify microorganisms, prevention, and control of infection, including vaccination, environmental and vector control.
Evaluate the principles of antimicrobial chemotherapy, antimicrobial resistance, including the clinical application antibiotic, antiviral, antifungal and antiparasitic therapies.
Assess the principles and application of public health microbiology, including epidemiology and control of infectious diseases plus the concept of One Health in relation to the prevention, prediction, detection, and response to global health threats from infectious diseases.

Content:

The module aims to provide an understanding of immunological disease and disorders, immunotherapy, prophylaxis plus transplantation immunology. Underlying immunological mechanisms are linked to the clinical features of the disorders. The range of laboratory tests used to diagnose and monitor treatment are evaluated with linked practical sessions. The features of a range of infectious diseases along with the mechanisms to diagnose plus treat will be taught with linked practical sessions and case study based examples.

The content of this module has been mapped to the IBMS QAA Benchmark requirements for:
Clinical Immunology (Clinical Laboratory Specialism) including principles of the function and measurement of effectors of the immune response; causes and consequences of abnormal immune function, neoplastic diseases and transplantation reactions together with their detection, diagnosis, treatment and monitoring; principles and practice of immunological techniques used for screening, diagnosis, treatment and monitoring of disease prophylaxis and immunotherapy.

Medical Microbiology (Clinical Laboratory Specialism) including pathogenic mechanisms of a range of microorganisms; public health microbiology (epidemiology and control of infectious diseases) and the concept of One Health; principles and practice of techniques used for screening, diagnosis, treatment and monitoring of a range of infectious diseases, involving a range of methods to detect and identify microorganisms, prevention and control of infection, including vaccination, environmental and vector control; antimicrobial chemotherapy, antimicrobial resistance (antibiotics, antivirals, antifungals, anti-parasitics).

Learning and Teaching Information:

A series of 8 x 2h lectures will cover the hypersensitivity, allergy testing, immunodeficiency, autoimmunity, immune prophylaxis, immunotherapy and transplantation immunology. These sessions will be supported by 6 x 2h practical sessions and 5 x 1h tutorials in semester 1.

In semester 2 a series of 8 x 2h lectures covering different infections by body system, including the respiratory tract, skin and mucosa, the gastrointestinal tract, the genito-urinary tract and the central nervous system. The characteristics of each system, the pathogenesis of each infection will be considered for each system. Hospital acquired infections and mechanisms of disease transmission will also be covered. These sessions will be supported by 9 x 2h practical sessions and 5 x 1h tutorials in semester 2.

Lectures
Hours: 32
Intended Group Size: Full Cohort

Practical sessions
Hours: 30
Intended Group Size: Full Cohort

Tutorials
Hours: 10
Intended Group Size: Max 20

Guided independent study
Hours: 228

Further details relating to assessment
The Clinical Immunology Essay assignment will be set in early Semester 1 and will focus on applying knowledge of the subject learned during the module to answering a case related question. Students will need to submit the completed assignment at the end of semester 1.

The Infectious Disease Practical portfolio will be based on the Clinical Microbiology selected practical sessions taught in Semester 2 and students will be informed of the selected sessions at the start of Semester 2. The assessment will include analysis of data generated during each of the selected practical sessions and critical analysis of the meaning of the results with reference to the case demographics given for each practical. Case study information and details of data to be analysed will be provided for each of the selected practical sessions and students will be required to complete the data analysis and critical analysis as guided independent study and then submit a portfolio of the completed work from all of the selected practical sessions at the end of semester 2.

Other Information
The Institute of Biomedical Science (IBMS) professional body requires students to achieve a pass mark in all assessment components for modules that cover the clinical laboratory sciences subject areas including this one. Since laboratory practical sessions contribute towards assessments these sessions should be considered compulsory. Condonement/compensation will not be permitted for this module, that contributes significantly to the benchmark statement and have learning outcomes that students achieve that cannot be evidenced elsewhere for the accreditation of the degree.

Assessment:

Fact File

Module Coordinator - PRS_CODE=
Level - 5
Credit Value - 30
Pre-Requisites - NONE
Semester(s) Offered -